| Alabama | Richard Shelby | Democratic | Re-elected, 64.8% | Richard Sellars (Republican) 33.1% Jerome Shockley (Libertarian) 2.0% |
| Alaska | Frank Murkowski | Republican | Re-elected, 53.0% | Tony Smith (Democratic) 38.4% Mary Jordan (Green) 8.4% |
| Arizona | John McCain | Republican | Re-elected, 55.8% | Claire Sargent (Democratic) 31.6% Evan Mecham (Independent) 10.5% Kiana Delamare (Libertarian) 1.6% Ed Finkelstein (New Alliance) 0.5% |
| Arkansas | Dale Bumpers | Democratic | Re-elected, 60.2% | Mike Huckabee (Republican) 39.8% |
| California (special[1]) | John F. Seymour | Republican | Defeated, 38.0% | Dianne Feinstein (Democratic) 54.3% Gerald Horne (Peace & Freedom) 2.8% Paul Meeuwenberg (American Ind.) 2.6% Richard B. Boddie (Libertarian) 2.3% |
| California | Alan Cranston | Democratic | Retired, Democratic victory | Barbara Boxer (Democratic) 47.9% Bruce Herschensohn (Republican) 43.0% Jerome McCready American Ind. 3.5% Genevieve Torres (Peace & Freedom) 3.5% June R. Genis (Libertarian) 2.2% |
| Colorado | Tim Wirth | Democratic | Retired, Democratic victory | Ben Nighthorse Campbell (Democratic) 51.8% Terry Considine (Republican) 42.7% Richard Grimes (Independent) 2.7% Matt Noah (Christian Pro-Life) 1.5% Dan Winters (Independent) 1.3% |
| Connecticut | Christopher Dodd | Democratic | Re-elected, 58.8% | Brook Johnson (Republican) 38.1% Richard D. Gregory (Concerned Citizens) 2.4% Howard A. Grayson, Jr. (Libertarian) 0.7% |
| Florida | Bob Graham | Democratic | Re-elected, 65.4% | James W. Grant (Republican) 34.6% |
| Georgia | Wyche Fowler | Democratic | Advanced in primary, 49.2%, Defeated in runoff, 49.4% | Paul Coverdell (Republican) 47.7%, 50.6% Jim Hudson (Libertarian) 3.1% |
| Hawaii | Daniel Inouye | Democratic | Re-elected, 57.3% | Rick Reed (Republican) 26.9% Linda Martin (Green) 13.7% Richard O. Rowland (Libertarian) 2.1% |
| Idaho | Steve Symms | Republican | Retired, Republican victory | Dirk Kempthorne (Republican) 56.5% Richard H. Stallings (Democratic) 43.5% |
| Illinois | Alan J. Dixon | Democratic | Defeated in primary, Democratic victory | Carol Moseley-Braun (Democratic) 53.3% Richard S. Williamson (Republican) 43.1% Chad Koppie (Conservative) 2.0% Andrew B. Spiegel (Libertarian) 0.7% Charles A. Winter (Natural Law) 0.3% Alan J. Port (New Alliance) 0.3% Kathleen Kaku (Socialist Workers) 0.2% John Justice (Populist) 0.2% |
| Indiana | Dan Coats | Republican | Re-elected, 57.3% | Joseph Hogsett (Democratic) 40.7% Steve Dillon (Libertarian) 1.6% Raymond Tirado (New Alliance) 0.3% |
| Iowa | Chuck Grassley | Republican | Re-elected, 69.6% | Jean Lloyd-Jones (Democratic) 27.2% Stuart Zimmerman (Natural Law) 1.3% Sue Atkinson (Independent) 0.5% Mel Boring (Independent) 0.4% Rosanne Freeburg (Independent) 0.4% Carl Eric Olsen (Grassroots) 0.3% Richard O'Dell Hughes (Independent) 0.2% Cleve Andrew Pulley (Socialist Workers) 0.1% |
| Kansas | Bob Dole | Republican | Re-elected, 62.7% | Gloria O'Dell (Democratic) 31.0% Christina Campbell-Cline (Independent) 4.0% Mark B. Kirk (Libertarian) 2.2% |
| Kentucky | Wendell H. Ford | Democratic | Re-elected, 62.9% | David Williams (Republican) 35.8% James Ridenour (Libertarian) 1.3% |
| Louisiana | John Breaux | Democratic | Re-elected in primary |
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| Maryland | Barbara Mikulski | Democratic | Re-elected, 71.0% | Alan Keyes (Republican) 29.0% |
| Missouri | Kit Bond | Republican | Re-elected, 51.9% | Geri Rothman-Serot (Democratic) 44.9% Jeanne Bojarski (Libertarian) 3.2% |
| Nevada | Harry Reid | Democratic | Re-elected, 51.0% | Demar Dahl (Republican) 40.2% None of These Candidates 2.6% Joe Garcia (Independent American) 2.3% Lois Avery (Natural Law) 1.5% H. Kent Cromwell (Libertarian) 1.5% Harry Tootle (Populist) 0.9% |
| New Hampshire | Warren Rudman | Republican | Retired, Republican victory | Judd Gregg (Republican) 48.2% John Rauh (Democratic) 45.3% K. Alexander (Libertarian) 3.5% |
| New York | Al D'Amato | Republican | Re-elected, 44.7% | Robert Abrams (Democratic) 43.6% Norma Segal (Libertarian) 1.5% Mohammad T. Mehdi (New Alliance) 0.8% Stanley Nelson (Natural Law) 0.3% Ed Warren (Socialist Workers) 0.2% |
| North Carolina | Terry Sanford | Democratic | Defeated, 46.3% | Lauch Faircloth (Republican) 50.4% Bobby Emory (Libertarian) 3.3% |
| North Dakota (Special[2]) | Jocelyn Burdick | Democratic | Retired, Democratic victory | Kent Conrad (Democratic) 63.3% Jack Dalrymple (Republican) 33.7% Darold Larson (Independent) 3.0% |
| North Dakota | Kent Conrad | Democratic | Retired, Democratic victory | Byron Dorgan (Democratic) 59.0% Steve Sydness (Republican) 38.9% Tom Asbridge (Independent) 2.1% |
| Ohio | John Glenn | Democratic | Re-elected, 51.0% | Mike DeWine (Republican) 42.3% Martha Grevatt (Independent) 6.7% |
| Oklahoma | Don Nickles | Republican | Re-elected, 58.5% | Steve Lewis (Democratic) 38.2% Roy V. Edwards (Independent) 1.6% Thomas D. Ledgerwood II (Independent) 1.6% |
| Oregon | Bob Packwood | Republican | Re-elected, 52.1% | Les AuCoin (Democratic) 46.5% |
| Pennsylvania | Arlen Specter | Republican | Re-elected, 49.1% | Lynn Yeakel (Democratic) 46.3% John Perry III (Independent) 4.6% |
| South Carolina | Ernest Hollings | Democratic | Re-elected, 50.1% | Thomas F. Hartnett (Republican) 46.9% Mark Johnson (Libertarian) 1.9% Robert Barnwell Clarkson II (American) 1.0% |
| South Dakota | Tom Daschle | Democratic | Re-elected, 64.9% | Charlene Haar (Republican) 32.5% Gus Hercules (Libertarian) 1.3% Kent Hyde (Independent) 1.3% |
| Utah | Jake Garn | Republican | Retired, Republican victory | Robert Bennett (Republican) 55.4% Wayne Owens (Democratic) 39.7% Anita Morrow (Independent) 2.3% |
| Vermont | Patrick Leahy | Democratic | Re-elected, 54.2% | Jim Douglas (Republican) 43.3% Jerry Levy (Liberty Union) 1.8% Michael B. Godeck (Freedom for LaRouche) 0.6% |
| Washington | Brock Adams | Democratic | Retired, Democratic victory | Patty Murray (Democratic) 54.0% Rod Chandler (Republican) 46.0% |
| Wisconsin | Bob Kasten | Republican | Defeated, 46.0% | Russ Feingold (Democratic) 52.6% Patrick W. Johnson (Independent) 0.7% William Bittner (Libertarian) 0.4% Mervin A. Hanson, Sr. (Independent) 0.1% Robert L. Kundert (Independent) 0.1% Joseph Selliken (Independent) 0.1% |